Analysis of 5' flanking regions of the gamma globin genes from major African haplotype backgrounds associated with sickle cell disease.

There are at least three major African haplotype backgrounds on which the beta s mutation arises. Sequence changes in the immediate 5' flanking area of the gamma-globin genes may account for differences in fetal hemoglobin expression among the three haplotypes. We determined the sequence from -...

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Detalhes bibliográficos
Main Authors: Month, S R, Wood, R W, Trifillis, P T, Orchowski, P J, Sharon, B, Ballas, S K, Surrey, S, Schwartz, E
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC296433/
https://ncbi.nlm.nih.gov/pubmed/1688883
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