Human α3β4 Neuronal Nicotinic Receptors Show Different Stoichiometry if They Are Expressed in Xenopus Oocytes or Mammalian HEK293 Cells

BACKGROUND: The neuronal nicotinic receptors that mediate excitatory transmission in autonomic ganglia are thought to be formed mainly by the α3 and β4 subunits. Expressing this composition in oocytes fails to reproduce the properties of ganglionic receptors, which may also incorporate the α5 and/or...

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Main Authors: Krashia, Paraskevi, Moroni, Mirko, Broadbent, Steven, Hofmann, Giovanna, Kracun, Sebastian, Beato, Marco, Groot-Kormelink, Paul J., Sivilotti, Lucia G.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2010
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Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964301/
https://ncbi.nlm.nih.gov/pubmed/21049012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013611
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