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Human α3β4 Neuronal Nicotinic Receptors Show Different Stoichiometry if They Are Expressed in Xenopus Oocytes or Mammalian HEK293 Cells

BACKGROUND: The neuronal nicotinic receptors that mediate excitatory transmission in autonomic ganglia are thought to be formed mainly by the α3 and β4 subunits. Expressing this composition in oocytes fails to reproduce the properties of ganglionic receptors, which may also incorporate the α5 and/or...

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Bibliografiske detaljer
Main Authors: Krashia, Paraskevi, Moroni, Mirko, Broadbent, Steven, Hofmann, Giovanna, Kracun, Sebastian, Beato, Marco, Groot-Kormelink, Paul J., Sivilotti, Lucia G.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964301/
https://ncbi.nlm.nih.gov/pubmed/21049012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013611
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