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Elicitation of structure-specific antibodies by epitope scaffolds
Elicitation of antibodies against targets that are immunorecessive, cryptic, or transient in their native context has been a challenge for vaccine design. Here we demonstrate the elicitation of structure-specific antibodies against the HIV-1 gp41 epitope of the broadly neutralizing antibody 2F5. Thi...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2964213/ https://ncbi.nlm.nih.gov/pubmed/20876137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004728107 |
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