Inhibition of brain tumor growth by intravenous poly(β-l-malic acid) nanobioconjugate with pH-dependent drug release

Effective treatment of brain neurological disorders such as Alzheimer's disease, multiple sclerosis, or tumors should be possible with drug delivery through blood–brain barrier (BBB) or blood–brain tumor barrier (BTB) and targeting specific types of brain cells with drug release into the cell c...

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Hlavní autoři: Ding, Hui, Inoue, Satoshi, Ljubimov, Alexander V., Patil, Rameshwar, Portilla-Arias, Jose, Hu, Jinwei, Konda, Bindu, Wawrowsky, Kolja A., Fujita, Manabu, Karabalin, Natalya, Sasaki, Takako, Black, Keith L., Holler, Eggehard, Ljubimova, Julia Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964197/
https://ncbi.nlm.nih.gov/pubmed/20921419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003919107
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