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Endocytosis is required for Toll signaling and shaping of the Dorsal/NF-κB morphogen gradient during Drosophila embryogenesis

Dorsoventral cell fate in the Drosophila embryo is specified by activation of the Toll receptor, leading to a ventral-to-dorsal gradient across nuclei of the NF-κB transcription factor Dorsal. Toll receptor has been investigated genetically, molecularly, and immunohistologically, but much less is kn...

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Détails bibliographiques
Auteurs principaux: Lund, Viktor K., DeLotto, Yvonne, DeLotto, Robert
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964194/
https://ncbi.nlm.nih.gov/pubmed/20921412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009157107
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