The C. elegans peroxidasin PXN-2 is essential for embryonic morphogenesis and inhibits adult axon regeneration

Peroxidasins form a highly conserved family of extracellular peroxidases of unknown cellular function. We identified the C. elegans peroxidasin PXN-2 in screens for mutants defective in embryonic morphogenesis. We find that PXN-2 is essential for specific stages of embryonic morphogenesis and muscle...

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Bibliographic Details
Main Authors: Gotenstein, Jennifer R., Swale, Ryann E., Fukuda, Tetsuko, Wu, Zilu, Giurumescu, Claudiu A., Goncharov, Alexandr, Jin, Yishi, Chisholm, Andrew D.
Format: Artigo
Language:Inglês
Published: Company of Biologists 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964093/
https://ncbi.nlm.nih.gov/pubmed/20876652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.049189
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