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Transforming acidic coiled-coil protein-3 (Tacc3) acts as a negative regulator of Notch signaling through binding to CDC10 /Ankyrin repeats

We have identified the transforming acidic coiled-coil protein-3 (Tacc3) as a binding partner for Notch4/Int3 and were able to show that it binds to the intracellular domain (ICD) of all members of the Notch receptor family. Members of the Tacc family reside at the centrosomes and associates with mi...

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Detalhes bibliográficos
Main Authors: Bargo, Sharon, Raafat, Ahmed, McCurdy, David, Amirjazil, Idean, Shu, Youmin, Traicoff, June, Plant, Joshua, Vonderhaar, Barbara K., Callahan, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964058/
https://ncbi.nlm.nih.gov/pubmed/20804727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.08.111
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