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Interferon gamma drastically modifies the regulation of interleukin 1 genes by endotoxin in U937 cells.

IL-1 alpha, IL-1 beta, and tumor necrosis factor alpha (TNF-alpha) gene expression is induced by LPS (endotoxin) in monocytes/macrophages and in some monocytic cell lines. IFN gamma and 1 alpha,25-dihydroxyvitamin D3 (1,25[OH]2D3) are important macrophage-activating factors. They induce changes in t...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Ucla, C, Roux-Lombard, P, Fey, S, Dayer, J M, Mach, B
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1990
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296404/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2104878/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114411
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