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Interferon gamma drastically modifies the regulation of interleukin 1 genes by endotoxin in U937 cells.
IL-1 alpha, IL-1 beta, and tumor necrosis factor alpha (TNF-alpha) gene expression is induced by LPS (endotoxin) in monocytes/macrophages and in some monocytic cell lines. IFN gamma and 1 alpha,25-dihydroxyvitamin D3 (1,25[OH]2D3) are important macrophage-activating factors. They induce changes in t...
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| Udgivet i: | J Clin Invest |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1990
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296404/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2104878/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114411 |
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