Impaired mitochondrial beta-oxidation in a patient with an abnormality of the respiratory chain. Studies in skeletal muscle mitochondria.

Defects of complex I of the mitochondrial respiratory chain are important causes of neurological disease. We report studies that demonstrate a severe deficiency of complex I activity with less severe abnormalities of complexes III and IV (less than 5, 63, and 30% of control values, respectively) in...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Watmough, N J, Bindoff, L A, Birch-Machin, M A, Jackson, S, Bartlett, K, Ragan, C I, Poulton, J, Gardiner, R M, Sherratt, H S, Turnbull, D M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296403/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2153151/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114409
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