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SS-31 modification alleviates ferroptosis induced by superparamagnetic iron oxide nanoparticles in hypoxia/reoxygenation cardiomyocytes

Superparamagnetic iron oxide nanoparticles (SPION) are widely used in cardiovascular applications. However, their potential to induce ferroptosis in myocardial cells post-ischemia-reperfusion hinders clinical adoption. We investigated the mechanisms behind SPION-induced cytotoxicity in myocardial ce...

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Principais autores: Qizheng Lu, Xiaobo Yao, Hao Zheng, Jinbo Ou, Jieyun You, Qi Zhang, Wei Guo, Jing Xu, Li Geng, Qinghua Liu, Ning Pei, Yongyong Gong, Hongming Zhu, Yunli Shen
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2024-10-01
Series:Heliyon
Assuntos:
Superparamagnetic iron oxide nanoparticles (SPION)
SS-31
Ferroptosis
Cardiotoxicity
Mitochondria
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2405844024146154
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