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Atrial natriuretic peptide attenuates the development of pulmonary hypertension in rats adapted to chronic hypoxia.

To test the hypothesis that chronic infusion of atrial natriuretic peptide (ANP) instituted before hypoxic exposure attenuates the development of pulmonary hypertension in hypoxia adapted rats, ANP (0.2 and 1.0 microgram/h) or vehicle was administered intravenously via osmotic minipump for 4 wk begi...

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Udgivet i:J Clin Invest
Principais autores: Jin, H, Yang, R H, Chen, Y F, Jackson, R M, Oparil, S
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296394/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2136863/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114400
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