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POSH is an Intracellular Signal Transducer for the Axon Outgrowth Inhibitor Nogo66

Myelin-derived inhibitors limit axon outgrowth and plasticity during development and in the adult mammalian CNS. Nogo66, a functional domain of the myelin-derived inhibitor NogoA, signals through the PirB receptor to inhibit axon outgrowth. The signaling pathway mobilized by Nogo66 engagement of Pir...

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Autori principali: Dickson, Heather M., Zurawski, Jonathan, Zhang, Huanqing, Turner, David L., Vojtek, Anne B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963859/
https://ncbi.nlm.nih.gov/pubmed/20926658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1324-10.2010
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