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Cannabinoid receptor type 2 (CB2) deficiency alters atherosclerotic lesion formation in hyperlipidemic Ldlr-null mice

OBJECTIVE: To determine if cannabinoid receptor 2 (CB2) plays a role in atherosclerosis, we investigated the effects of systemic CB2 gene deletion on hyperlipidemia-induced atherogenesis in low density lipoprotein receptor-deficient (Ldlr(−/−)) mice. METHODS AND RESULTS: Ldlr(−/−) and CB2/Ldlr doubl...

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Bibliografiske detaljer
Main Authors: Netherland, Courtney D., Pickle, Theresa G., Bales, Alicia, Thewke, Douglas P.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963728/
https://ncbi.nlm.nih.gov/pubmed/20846652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2010.07.060
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