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Germline Met Mutations in Mice Reveal Mutation- and Background-Associated Differences in Tumor Profiles
BACKGROUND: The receptor tyrosine kinase Met is involved in the progression and metastasis of numerous human cancers. Although overexpression and autocrine activation of the Met signaling pathway are commonly found in human cancers, mutational activation of Met has been observed in small cell and no...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2010
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2963642/ https://ncbi.nlm.nih.gov/pubmed/21049054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013586 |
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