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Germline Met Mutations in Mice Reveal Mutation- and Background-Associated Differences in Tumor Profiles

BACKGROUND: The receptor tyrosine kinase Met is involved in the progression and metastasis of numerous human cancers. Although overexpression and autocrine activation of the Met signaling pathway are commonly found in human cancers, mutational activation of Met has been observed in small cell and no...

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Detalhes bibliográficos
Main Authors: Graveel, Carrie R., DeGroot, Jack D., Sigler, Robert E., Vande Woude, George F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963642/
https://ncbi.nlm.nih.gov/pubmed/21049054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013586
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