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No evidence for serological autoimmunity to islet cell heat shock proteins in insulin dependent diabetes.

Recent studies in nonobese diabetic mice have implicated the autoimmune destruction of pancreatic islet cells with immunity to a beta cell protein cross-reactive to Mycobacterium tuberculosis heat shock protein 65 (hsp 65). Therefore, our studies examined serological immunity to islet cell hsp in hu...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Atkinson, M A, Holmes, L A, Scharp, D W, Lacy, P E, Maclaren, N K
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296364/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1991854/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115051
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