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Computationally efficient flux variability analysis

BACKGROUND: Flux variability analysis is often used to determine robustness of metabolic models in various simulation conditions. However, its use has been somehow limited by the long computation time compared to other constraint-based modeling methods. RESULTS: We present an open source implementat...

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Detalhes bibliográficos
Main Authors: Gudmundsson, Steinn, Thiele, Ines
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963619/
https://ncbi.nlm.nih.gov/pubmed/20920235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-489
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