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Moderation of Calpain Activity Promotes Neovascular Integration and Lumen Formation during VEGF-Induced Pathological Angiogenesis

BACKGROUND: Successful neovascularization requires that sprouting endothelial cells (ECs) integrate to form new vascular networks. However, architecturally defective, poorly integrated vessels with blind ends are typical of pathological angiogenesis induced by vascular endothelial growth factor-A (V...

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Библиографические подробности
Главные авторы: Hoang, Mien V., Nagy, Janice A., Fox, Joan E. B., Senger, Donald R.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963609/
https://ncbi.nlm.nih.gov/pubmed/21049044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013612
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