Moderation of Calpain Activity Promotes Neovascular Integration and Lumen Formation during VEGF-Induced Pathological Angiogenesis

BACKGROUND: Successful neovascularization requires that sprouting endothelial cells (ECs) integrate to form new vascular networks. However, architecturally defective, poorly integrated vessels with blind ends are typical of pathological angiogenesis induced by vascular endothelial growth factor-A (V...

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Detalles Bibliográficos
Main Authors: Hoang, Mien V., Nagy, Janice A., Fox, Joan E. B., Senger, Donald R.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963609/
https://ncbi.nlm.nih.gov/pubmed/21049044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013612
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