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Defective insulin response of cyclic adenosine monophosphate-dependent protein kinase in insulin-resistant humans.

Insulin-stimulated glycogen synthase activity in human muscle correlates with insulin-mediated glucose disposal and is reduced in insulin-resistant subjects. Inhibition of the cyclic AMP-dependent protein kinase (A-kinase) is considered as a possible mechanism of insulin action for glycogen synthase...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Kida, Y, Nyomba, B L, Bogardus, C, Mott, D M
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1991
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296358/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1846879/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115045
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