Limited B cell repertoire in severe combined immunodeficient mice engrafted with peripheral blood mononuclear cells derived from immunodeficient or normal humans.

The ability to engraft human PBMC or fetal tissue immune cells in the severe combined immunodeficient (SCID) mouse has created a need for characterization of these systems and their application to disease models. We demonstrate that SCID mice reconstituted with PBMC support the growth and differenti...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Saxon, A, Macy, E, Denis, K, Tary-Lehmann, M, Witte, O, Braun, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1991
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Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296356/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1991850/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115043
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