Insights into Function, Catalytic Mechanism, and Fold Evolution of Selenoprotein Methionine Sulfoxide Reductase B1 through Structural Analysis

Methionine sulfoxide reductases protect cells by repairing oxidatively damaged methionine residues in proteins. Here, we report the first three-dimensional structure of the mammalian selenoprotein methionine sulfoxide reductase B1 (MsrB1), determined by high resolution NMR spectroscopy. Heteronuclea...

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Bibliographic Details
Main Authors: Aachmann, Finn L., Sal, Lena S., Kim, Hwa-Young, Marino, Stefano M., Gladyshev, Vadim N., Dikiy, Alexander
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963413/
https://ncbi.nlm.nih.gov/pubmed/20605785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.132308
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