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Insights into Function, Catalytic Mechanism, and Fold Evolution of Selenoprotein Methionine Sulfoxide Reductase B1 through Structural Analysis

Methionine sulfoxide reductases protect cells by repairing oxidatively damaged methionine residues in proteins. Here, we report the first three-dimensional structure of the mammalian selenoprotein methionine sulfoxide reductase B1 (MsrB1), determined by high resolution NMR spectroscopy. Heteronuclea...

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Bibliografiske detaljer
Main Authors: Aachmann, Finn L., Sal, Lena S., Kim, Hwa-Young, Marino, Stefano M., Gladyshev, Vadim N., Dikiy, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963413/
https://ncbi.nlm.nih.gov/pubmed/20605785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.132308
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