Insights into Function, Catalytic Mechanism, and Fold Evolution of Selenoprotein Methionine Sulfoxide Reductase B1 through Structural Analysis

Methionine sulfoxide reductases protect cells by repairing oxidatively damaged methionine residues in proteins. Here, we report the first three-dimensional structure of the mammalian selenoprotein methionine sulfoxide reductase B1 (MsrB1), determined by high resolution NMR spectroscopy. Heteronuclea...

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Autores principales: Aachmann, Finn L., Sal, Lena S., Kim, Hwa-Young, Marino, Stefano M., Gladyshev, Vadim N., Dikiy, Alexander
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Protein Structure and Folding
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963413/
https://ncbi.nlm.nih.gov/pubmed/20605785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.132308
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