Heme Amplifies the Innate Immune Response to Microbial Molecules through Spleen Tyrosine Kinase (Syk)-dependent Reactive Oxygen Species Generation

Infectious diseases that cause hemolysis are among the most threatening human diseases, because of severity and/or global distribution. In these conditions, hemeproteins and heme are released, but whether heme affects the inflammatory response to microorganism molecules remains to be characterized....

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Bibliografische gegevens
Hoofdauteurs: Fernandez, Patricia L., Dutra, Fabianno F., Alves, Letícia, Figueiredo, Rodrigo T., Mourão-Sa, Diego, Fortes, Guilherme B., Bergstrand, Sophie, Lönn, David, Cevallos, Ricardo R., Pereira, Renata M. S., Lopes, Ulisses G., Travassos, Leonardo H., Paiva, Claudia N., Bozza, Marcelo T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2010
Onderwerpen:
Immunology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963404/
https://ncbi.nlm.nih.gov/pubmed/20729208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.146076
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