Peroxisome Proliferator-activated Receptor γ Coactivator 1α (PGC-1α) Promotes Skeletal Muscle Lipid Refueling in Vivo by Activating de Novo Lipogenesis and the Pentose Phosphate Pathway

Exercise induces a pleiotropic adaptive response in skeletal muscle, largely through peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α). PGC-1α enhances lipid oxidation and thereby provides energy for sustained muscle contraction. Its potential implication in promoting muscle refue...

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Autores principales: Summermatter, Serge, Baum, Oliver, Santos, Gesa, Hoppeler, Hans, Handschin, Christoph
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Metabolism
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963391/
https://ncbi.nlm.nih.gov/pubmed/20716531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.145995
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