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Pax6 Controls the Expression of Critical Genes Involved in Pancreatic α Cell Differentiation and Function
The paired box homeodomain Pax6 is crucial for endocrine cell development and function and plays an essential role in glucose homeostasis. Indeed, mutations of Pax6 are associated with diabetic phenotype. Importantly, homozygous mutant mice for Pax6 are characterized by markedly decreased β and δ ce...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2963382/ https://ncbi.nlm.nih.gov/pubmed/20592023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.147215 |
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