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Porphyromonas gingivalis Peptidoglycans Induce Excessive Activation of the Innate Immune System in Silkworm Larvae

Porphyromonas gingivalis, a pathogen that causes inflammation in human periodontal tissue, killed silkworm (Bombyx mori, Lepidoptera) larvae when injected into the blood (hemolymph). Silkworm lethality was not rescued by antibiotic treatment, and heat-killed bacteria were also lethal. Heat-killed ba...

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Bibliographische Detailangaben
Hauptverfasser: Ishii, Kenichi, Hamamoto, Hiroshi, Imamura, Katsutoshi, Adachi, Tatsuo, Shoji, Mikio, Nakayama, Koji, Sekimizu, Kazuhisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963355/
https://ncbi.nlm.nih.gov/pubmed/20702417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.112987
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