Editing of Epstein-Barr Virus-encoded BART6 MicroRNAs Controls Their Dicer Targeting and Consequently Affects Viral Latency

Certain primary transcripts of miRNA (pri-microRNAs) undergo RNA editing that converts adenosine to inosine. The Epstein-Barr virus (EBV) genome encodes multiple microRNA genes of its own. Here we report that primary transcripts of ebv-miR-BART6 (pri-miR-BART6) are edited in latently EBV-infected ce...

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Detalles Bibliográficos
Autores principales: Iizasa, Hisashi, Wulff, Bjorn-Erik, Alla, Nageswara R., Maragkakis, Manolis, Megraw, Molly, Hatzigeorgiou, Artemis, Iwakiri, Dai, Takada, Kenzo, Wiedmer, Andreas, Showe, Louise, Lieberman, Paul, Nishikura, Kazuko
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
RNA
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963350/
https://ncbi.nlm.nih.gov/pubmed/20716523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.138362
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