Neutralization of endogenous IL-1 receptor antagonist exacerbates and prolongs inflammation in rabbit immune colitis.

Administration of exogenous interleukin-1 receptor antagonist (IL-1ra) is effective in reducing the severity of disease in animal models of acute inflammation. However, the function of endogenous IL-1ra in this process, is not yet known. We investigated the pathophysiological role of IL-1ra in a rab...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Ferretti, M, Casini-Raggi, V, Pizarro, T T, Eisenberg, S P, Nast, C C, Cominelli, F
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296330/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8040288/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117345
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