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Neutralization of endogenous IL-1 receptor antagonist exacerbates and prolongs inflammation in rabbit immune colitis.

Administration of exogenous interleukin-1 receptor antagonist (IL-1ra) is effective in reducing the severity of disease in animal models of acute inflammation. However, the function of endogenous IL-1ra in this process, is not yet known. We investigated the pathophysiological role of IL-1ra in a rab...

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Detalhes bibliográficos
Main Authors: Ferretti, M, Casini-Raggi, V, Pizarro, T T, Eisenberg, S P, Nast, C C, Cominelli, F
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC296330/
https://ncbi.nlm.nih.gov/pubmed/8040288
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