Genotoxicity Revaluation of Three Commercial Nitroheterocyclic Drugs: Nifurtimox, Benznidazole, and Metronidazole

Nitroheterocyclic compounds are widely used as therapeutic agents against a variety of protozoan and bacterial infections. However, the literature on these compounds, suspected of being carcinogens, is widely controversial. In this study, cytotoxic and genotoxic potential of three drugs, Nifurtimox...

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Detalhes bibliográficos
Main Authors: Buschini, Annamaria, Ferrarini, Lisa, Franzoni, Susanna, Galati, Serena, Lazzaretti, Mirca, Mussi, Francesca, Northfleet de Albuquerque, Cristina, Maria Araújo Domingues Zucchi, Tânia, Poli, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963127/
https://ncbi.nlm.nih.gov/pubmed/20981287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/463575
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