Cystic fibrosis transmembrane conductance regulator mutations that disrupt nucleotide binding.

Increasing evidence suggests heterogeneity in the molecular pathogenesis of cystic fibrosis (CF). Mutations such as deletion of phenylalanine at position 508 (delta F508) within the cystic fibrosis transmembrane conductance regulator (CFTR), for example, appear to cause disease by abrogating normal...

Description complète

Détails bibliographiques

Publié dans:	J Clin Invest
Auteurs principaux:	Logan, J, Hiestand, D, Daram, P, Huang, Z, Muccio, D D, Hartman, J, Haley, B, Cook, W J, Sorscher, E J
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1994
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296301/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7518829/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117311
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!