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Catalytic Enantioselective Alkylative Dearomatization-Annulation: Total Synthesis and Absolute Configuration Assignment of Hyperibone K

[Image: see text] The asymmetric total synthesis of the polyprenylated acylphloroglucinol hyperibone K has been achieved using an enantioselective alkylative dearomatization-annulation process. NMR and computational studies were employed to probe the mode of action of a chiral phase-transfer (ion pa...

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Autors principals: Qi, Ji, Beeler, Aaron B., Zhang, Qiang, Porco, John A.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962984/
https://ncbi.nlm.nih.gov/pubmed/20831187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1057828
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