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ApoE−/− PGC-1α−/− Mice Display Reduced IL-18 Levels and Do Not Develop Enhanced Atherosclerosis

BACKGROUND: Atherosclerosis is a chronic inflammatory disease that evolves from the interaction of activated endothelial cells, macrophages, lymphocytes and modified lipoproteins (LDLs). In the last years many molecules with crucial metabolic functions have been shown to prevent important steps in t...

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Detalhes bibliográficos
Main Authors: Stein, Sokrates, Lohmann, Christine, Handschin, Christoph, Stenfeldt, Elin, Borén, Jan, Lüscher, Thomas F., Matter, Christian M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962638/
https://ncbi.nlm.nih.gov/pubmed/21042583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013539
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