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Expansion of Human Cord Blood Hematopoietic Stem Cells for Transplantation

A recent Science paper reported a purine derivative that expands human cord blood hematopoietic stem cells in culture (Boitano et al., 2010) by antagonizing the aryl hydrocarbon receptor. Major problems need to be overcome before ex vivo HSC expansion can be used clinically.

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Bibliographische Detailangaben
Hauptverfasser: Chou, Song, Chu, Pat, Hwang, William, Lodish, Harvey
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962561/
https://ncbi.nlm.nih.gov/pubmed/20887947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.09.001
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