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Ras Homolog Enriched in Brain (Rheb) Enhances Apoptotic Signaling

Rheb is a homolog of Ras GTPase that regulates cell growth, proliferation, and regeneration via mammalian target of rapamycin (mTOR). Because of the well established potential of activated Ras to promote survival, we sought to investigate the ability of Rheb signaling to phenocopy Ras. We found that...

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Detalhes bibliográficos
Main Authors: Karassek, Sascha, Berghaus, Carsten, Schwarten, Melanie, Goemans, Christoph G., Ohse, Nadine, Kock, Gerd, Jockers, Katharina, Neumann, Sebastian, Gottfried, Sebastian, Herrmann, Christian, Heumann, Rolf, Stoll, Raphael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962498/
https://ncbi.nlm.nih.gov/pubmed/20685651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.095968
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