Improved Green Fluorescent Protein Reporter Gene-Based Microplate Screening for Antituberculosis Compounds by Utilizing an Acetamidase Promoter

The green fluorescent protein (GFP) gene offers many advantages as a viability reporter for high-throughput antimicrobial drug screening. However, screening for antituberculosis compounds by using GFP driven by the heat shock promoter, hsp60, has been of limited utility due to the low signal-to-nois...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Changsen, Chartchai, Franzblau, Scott G., Palittapongarnpim, Prasit
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2003
Subjects:
Susceptibility
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296217/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14638465/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.12.3682-3687.2003
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