Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice.

Apolipoprotein E (apo E)-deficient mice are severely hypercholesterolemic and develop advanced atheromas independent of diet. The C57BL/6 strain differs from most inbred strains by having lower HDL concentrations and a high risk of developing early atherosclerotic lesions when fed an atherogenic die...

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Detalles Bibliográficos

Publicado en:	J Clin Invest
Principais autores:	Pászty, C, Maeda, N, Verstuyft, J, Rubin, E M
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical Investigation 1994
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296173/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8040345/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117412
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