Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice.
Apolipoprotein E (apo E)-deficient mice are severely hypercholesterolemic and develop advanced atheromas independent of diet. The C57BL/6 strain differs from most inbred strains by having lower HDL concentrations and a high risk of developing early atherosclerotic lesions when fed an atherogenic die...
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| Udgivet i: | J Clin Invest |
|---|---|
| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1994
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296173/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8040345/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117412 |
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