Repression of Fanconi anemia gene (FACC) expression inhibits growth of hematopoietic progenitor cells.

Bone marrow failure is a consistent feature of Fanconi anemia (FA) but it is not known whether the bone marrow failure is a direct and specific result of the inherited mutation or a consequence of accumulated stem cell losses resulting from nonspecific DNA damage. We tested the hypothesis that the p...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Segal, G M, Magenis, R E, Brown, M, Keeble, W, Smith, T D, Heinrich, M C, Bagby, G C
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296166/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7518843/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117405
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