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Repression of Fanconi anemia gene (FACC) expression inhibits growth of hematopoietic progenitor cells.
Bone marrow failure is a consistent feature of Fanconi anemia (FA) but it is not known whether the bone marrow failure is a direct and specific result of the inherited mutation or a consequence of accumulated stem cell losses resulting from nonspecific DNA damage. We tested the hypothesis that the p...
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| Pubblicato in: | J Clin Invest |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
1994
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296166/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7518843/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117405 |
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