Selective response of human airway epithelia to luminal but not serosal solution hypertonicity. Possible role for proximal airway epithelia as an osmolality transducer.

The response of cultured human nasal epithelia to hypertonic bathing solutions was tested using ion-selective microelectrode and quantitative microscopy. Raised luminal, but not serosal, osmolality (+/- 150 mM mannitol) decreased Na+ absorption but did not induce Cl- secretion. Raised luminal osmola...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Willumsen, N J, Davis, C W, Boucher, R C
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1994
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296158/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8040333/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117397
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