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Herpes Simplex Virus 1 Mutant in Which the ICP0 HUL-1 E3 Ubiquitin Ligase Site Is Disrupted Stabilizes cdc34 but Degrades D-Type Cyclins and Exhibits Diminished Neurotoxicity

Herpes simplex virus type 1 (HSV-1) infected cell protein 0 (ICP0) is a multifunctional protein that functions as a promiscuous transactivator and promotes the degradation of multiple cellular proteins. In vitro studies indicated that it encodes two physically separated functional E3 ubiquitin ligas...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Hagglund, Ryan, Roizman, Bernard
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2003
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296091/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14645576/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.24.13194-13202.2003
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