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Varied Immunity Generated in Mice by DNA Vaccines with Large and Small Hepatitis Delta Antigens

Whether the hepatitis delta virus (HDV) DNA vaccine can induce anti-HDV antibodies has been debatable. The role of the isoprenylated motif of hepatitis delta antigens (HDAg) in the generation of immune responses following DNA-based immunization has never been studied. Plasmids p2577L, encoding large...

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Autors principals: Huang, Yi-Hsiang, Wu, Jaw-Ching, Hsu, Sheng-Chieh, Syu, Wan-Jr
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC296071/
https://ncbi.nlm.nih.gov/pubmed/14645554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.24.12980-12985.2003
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