Hepatitis Delta Virus RNA Encoding the Large Delta Antigen Cannot Sustain Replication due to Rapid Accumulation of Mutations Associated with RNA Editing

Hepatitis delta virus (HDV) contains two RNA species (HDV-S and HDV-L), which encode the small and large forms of hepatitis delta antigens (S- and L-HDAg), respectively. HDV-L RNA is a result of an RNA editing event occurring at an amber/W site of HDV-S RNA. RNA editing must be regulated to prevent...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Macnaughton, Thomas B., Li, Yi-Ija, Doughty, Alison L., Lai, Michael M. C.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2003
Предметы:
Replication
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254293/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14581541/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.22.12048-12056.2003
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