Multispecific Vaccine-Induced Mucosal Cytotoxic T Lymphocytes Reduce Acute-Phase Viral Replication but Fail in Long-Term Control of Simian Immunodeficiency Virus SIVmac239

Given the current difficulties generating vaccine-induced neutralizing antibodies to human immunodeficiency virus (HIV), the focus of the vaccine community has shifted toward creating cytotoxic-T-lymphocyte (CTL)-based vaccines. Recent reports of CTL-based vaccine trials in macaques challenged with...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Vogel, Thorsten U., Reynolds, Matthew R., Fuller, Deborah H., Vielhuber, Kathy, Shipley, Tim, Fuller, James T., Kunstman, Kevin J., Sutter, Gerd, Marthas, Marta L., Erfle, Volker, Wolinsky, Steven M., Wang, Chenxi, Allison, David B., Rud, Erling W., Wilson, Nancy, Montefiori, David, Altman, John D., Watkins, David I.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2003
Θέματα:
Vaccines and Antiviral Agents
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC296068/
https://ncbi.nlm.nih.gov/pubmed/14645590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.24.13348-13360.2003
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