Multispecific Vaccine-Induced Mucosal Cytotoxic T Lymphocytes Reduce Acute-Phase Viral Replication but Fail in Long-Term Control of Simian Immunodeficiency Virus SIVmac239

Given the current difficulties generating vaccine-induced neutralizing antibodies to human immunodeficiency virus (HIV), the focus of the vaccine community has shifted toward creating cytotoxic-T-lymphocyte (CTL)-based vaccines. Recent reports of CTL-based vaccine trials in macaques challenged with...

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Vogel, Thorsten U., Reynolds, Matthew R., Fuller, Deborah H., Vielhuber, Kathy, Shipley, Tim, Fuller, James T., Kunstman, Kevin J., Sutter, Gerd, Marthas, Marta L., Erfle, Volker, Wolinsky, Steven M., Wang, Chenxi, Allison, David B., Rud, Erling W., Wilson, Nancy, Montefiori, David, Altman, John D., Watkins, David I.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2003
Aiheet:
Vaccines and Antiviral Agents
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296068/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14645590/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.24.13348-13360.2003
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