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Multispecific Vaccine-Induced Mucosal Cytotoxic T Lymphocytes Reduce Acute-Phase Viral Replication but Fail in Long-Term Control of Simian Immunodeficiency Virus SIVmac239
Given the current difficulties generating vaccine-induced neutralizing antibodies to human immunodeficiency virus (HIV), the focus of the vaccine community has shifted toward creating cytotoxic-T-lymphocyte (CTL)-based vaccines. Recent reports of CTL-based vaccine trials in macaques challenged with...
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Prif Awduron: | , , , , , , , , , , , , , , , , , |
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Fformat: | Artigo |
Iaith: | Inglês |
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American Society for Microbiology
2003
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Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC296068/ https://ncbi.nlm.nih.gov/pubmed/14645590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.24.13348-13360.2003 |
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